NCT05227248已完成不适用
Evaluation of the Effects of Chocolate on Anatomy and Functionality of Retinal Blood Vessels
Querques Giuseppe2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2021年4月9日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Retinal perfusion
研究概览
简要总结
The study aims at evaluating the effect of dark chocolate consumption on anatomy and functionality of retinal blood vessels by comparing these same parameters after milk chocolate consumption.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Sequential
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age of 18 years or older
- •Healthy volunteers
- •No vascular diseases
- •No ocular diseases
- •Volunteers capable of understanding informed consent
排除标准
- •Patient unable to follow the instructions
- •Patient unable to come back for follow-up
- •opacity of lens, cornea, or vitreous
- •Allergies that contraindicate pupil dilation
- •Eye diseases
- •Myopia greater than -8.0 Diopter (D),
- •Hyperopia greater than 5.0 D
- •Astigmatism greater than -3.0 D
结局指标
主要结局
Retinal perfusion
时间窗: Baseline, 2 hours after intervention
Changes in retinal perfusion using Optical Coherence Tomography Angiography
Retinal vascular response
时间窗: Baseline, 2 hours after intervention
Changes in retinal vascular response to flicker stimulation using Dynamic Vessels Analysis and Retinal Vessels Analysis
次要结局
- Visual Acuity(Baseline, 2 hours after intervention)
研究者
Querques Giuseppe
Professor
Ospedale San Raffaele
研究点 (2)
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