Effect of Wheat Dextrin on Calcium and Magnesium Absorption
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 40
- 主要终点
- Calcium Absorption
研究概览
简要总结
To compare calcium and magnesium absorption within subjects with and without chronic consumption of wheat dextrin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Subjects will be generally healthy Caucasian females aged 19 and older with no known abnormalities of gastrointestinal function, and taking no medications that might alter absorptive performance. BMI will be between 19 and 31 kg/m2
排除标准
- 未提供
研究组 & 干预措施
placebo
Control cookies will contain no wheat dextrin and will be taken 3 times daily for 2 weeks.
干预措施: placebo (Dietary Supplement)
wheat dextrin
wheat dextrin (formulated according to the supporter's established method), will be baked in cookies providing three doses per day (≈5 gram of wheat dextrin in each dose)for 2 weeks.
干预措施: wheat dextrin (Dietary Supplement)
结局指标
主要结局
Calcium Absorption
时间窗: within 2-4 weeks
The calcium load to be tested will be 300 mg calcium from calcium and vitamin D fortified TropicanaTM orange juice extrinsically labeled with ≈3-7 μCi of 45Ca. The labeled orange juice will be ingested as part of a light meal, served as breakfast, after an overnight fast.
次要结局
- Magnesium absorption(within 2-4 weeks)