Sensory Maturation of Preterm Infants: From Visual Sensitivity to Multisensory Perception
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- visual stimulus detection with luminance
研究概览
简要总结
We aim to increase our knowledge of the impact of preterm birth on the maturation of the visual and auditory systems and on the development of multisensory perception
Specifically, we aim to evaluate the preterm infants' capabilities of detection and discrimination of different visual and auditory stimuli according to gestational age, post menstrual age and the duration of the postnatal life.
A secondary aim is to compare this competencies in preterm and full term control art term equivalent age.
The final aim is to optimize the hospital environment in order to make it correspond to the expectations and sensory abilities of very preterm infants.
Our hypothesis is that preterm birth exposes the infants to numerous atypical stimuli which could accelerate the processes of sensory maturation
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 23 Weeks 至 42 Weeks（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Newborn less than 32 weeks PMA hospitalized in the Hospital of Hautepierre, Strasbourg, France)
- •Consent obtained from both parents
- •Social insurance coverage
排除标准
- •Any known malformation
- •Brain lesions discovered on brain ultrasound (Intra-Ventricular hemorrhage grade III or IV periventricular Leukomalacia).
- •Unstable clinical State
- •Retinopathy Of Prematurity stage> 2 or in zone 1
- •Family history of abnormal color vision.
- •Abnormalities in auditory testing
- •Transfer to another hospital expected before 40 week PMA
研究组 & 干预措施
preterm infants
physiological data collection, behavioral, cerebral hemodynamics, physical environmental newborns studied in response to visual stimuli / auditory or visual-auditory calibrated
干预措施: collection data (Behavioral)
preterm infants
physiological data collection, behavioral, cerebral hemodynamics, physical environmental newborns studied in response to visual stimuli / auditory or visual-auditory calibrated
干预措施: IRM (Behavioral)
term infants
physiological data collection, behavioral, cerebral hemodynamics, physical environmental newborns studied in response to visual stimuli / auditory or visual-auditory calibrated
干预措施: IRM (Behavioral)
term infants
physiological data collection, behavioral, cerebral hemodynamics, physical environmental newborns studied in response to visual stimuli / auditory or visual-auditory calibrated
干预措施: collection data (Behavioral)
结局指标
主要结局
visual stimulus detection with luminance
时间窗: 3 months
in "green" condition in hospital, luminance ( 100 and 300 lux ) and color (blue- red-yellow- white) variables
auditory stimulus detection with parents voice
时间窗: 3 months
use parents voice, pure sound of 500 Hz
次要结局
- behavioral responsiveness to visual stimuli calibrated collected from video recordings(3 months)