Effect of 4 Weeks of Shuttle Run Training on Insulin Sensitivity in Sedentary Men
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Insulin sensitivity
研究概览
简要总结
A number of studies have shown that short duration, high intensity interval training can improve health-related outcomes, such as insulin sensitivity and cardiorespiratory fitness. However, these often use specialized equipment, such as cycle ergometers, which makes it difficult to roll these interventions out for wide-scale use in the general population. This study aims evaluate the effects of a high intensity shuttle running intervention on insulin sensitivity, fitness and related cardiometabolic risk factors in men who are currently inactive. Participants will be randomized into intervention (4 weeks of shuttle running) and control groups. We hypothesize that the shuttle running programme will result in improved insulin sensitivity, fitness and increased fat oxidation at rest compared with the control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •18-40 years
- •undertaking < 1 hour per week of planned exercise
排除标准
- •BMI > 35 kg/m2
- •Blood pressure > 160/90 mm Hg (on anti-hypertensive medication)
- •history of established coronary heart disease
- •family history of early cardiac death (<40 years)
结局指标
主要结局
Insulin sensitivity
时间窗: Change from baseline immediately post-intervention (4 weeks after baseline)
Assessed from glucose and insulin concentrations in fasted state and during oral glucose tolerance test.
次要结局
- Resting substrate utilization(Change from baseline immediately post-intervention (4 weeks after baseline))
- Endurance exercise performance(Change from baseline immediately post-intervention (4 weeks after baseline))
- Sprint exercise performance(Change from baseline immediately post-intervention (4 weeks after baseline))
- Body weight(Change from baseline immediately post-intervention (4 weeks after baseline))
- Waist circumference(Change from baseline immediately post-intervention (4 weeks after baseline))
- Percentage body fat(Change from baseline immediately post-intervention (4 weeks after baseline))
- Clustered Cardiometabolic Risk Score(Change from baseline immediately post-intervention (4 weeks after baseline))
研究者
Dr Jason Gill
Reader in Exercise Metabolism
University of Glasgow