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临床试验/NCT06882954
NCT06882954招募中不适用

The Management of Asymptomatic Carotid Stenosis: Monocentric Experience

Fondazione Policlinico Universitario Agostino Gemelli IRCCS1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2019年1月1日最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
500
试验地点
1
主要终点
Stroke rate

研究概览

简要总结

Carotid stenosis are asymptomatic if no hemispheric or retinal symptoms have appeared in the 6 months preceding the discovery of the stenosis. Asymptomatic carotid stenosis (ACS) accounts for about ¾ of all carotid lesions. The goal of treating carotid stenosis is to prevent a stroke. While carotid surgery is recommended in the elderly patients in cases of symptomatic carotid stenosis, that of ACS in patients over 75 years old, even when tight, remains subject to many controversies. Indeed, the debate, concerning the benefit to be expected from a surgical procedure or a possible angioplasty procedure, is not yet closed. The aim of our study, through a retrospective evaluation of the results of all consecutive carotid endarterectomy (CEA) and stenting in the participating center.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Asymptomatic carotid stenosis
  • Patient with degree of carotid stenosis greater than 80% measured by the maximum systolic velocity at the site of the stenosis which must have been greater than 250 cm/s
  • Ultrasound characteristics of a possibly unstable plaque

排除标准

  • Symptomatic carotid artery stenosis

结局指标

主要结局

Stroke rate

时间窗: Through study completion, an average of 1 year

Rate of stroke after the procedure

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

TINELLI GIOVANNI

Associate Professor of Vascular Surgery

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

研究点 (1)

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