CTRI/2025/03/082794尚未招募4 期
A Randomized double blinded trial to compare the hemodynamics of hyperbaric Ropivacaine with hyperbaric Bupivacaine in elective cesarean sections under spinal anesthesia
Dr nisha george1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2025年3月29日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To compare the vasopressor requirement in treating spinal anesthesia induced hypotension among Hyperbaric Ropivacaine with Hyperbaric Bupivacaine groups
研究概览
简要总结
A Double blinded randomized control trial to compare the hemodynamics and vasopressor requirement by using two local anesthetic agents 0.75% ropivacaine with 0.5% bupivacaine in patients undergoing elective cesarean section under spinal anesthesia anf to see the onset and level of motor and sensory blockade .
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Double Blind Double Dummy
入排标准
- 年龄范围
- 18.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- Female
入选标准
- •Participants with uncomplicated term singleton pregnancy undergoing elective cesarean delivery .
- •Participants belonging to American Society Of Anesthesiologist 3)Body weight at the time of delivery between 65kgs and 95kgs 4)Height betweeen 155 and 175 cms 5)Participants giving informed written and valid consent 6)Participants age between 18 and 35 years.
排除标准
- •Participants having hypertensive disorders of pregnancy and diabetes mellitus 2)Participants with cardiac,Cerebrovascular,renal disorders 3)Participants with oligohydramnios,Intrauterine growth retardartion 4)Participants having hypersensitivity to any of the study drugs 5)Participants with known contraindications to spinal anaesthesia.
结局指标
主要结局
To compare the vasopressor requirement in treating spinal anesthesia induced hypotension among Hyperbaric Ropivacaine with Hyperbaric Bupivacaine groups
时间窗: measuring heart rate blood pressure respiratory rate oxygen saturation will be monitored Blood pressure will be recorded at 2 min interval for 20 minutes & 10 minute intervals through out surgery
次要结局
- time of onset at peak level of sensory blockade duration of sensory blockonet of motor blockadverse efvents like nausea vomitting respiratory depression shivering(neonatal status will be assessed by APGAR score at 1min & 5 min and VAS Score to assess the intensity of podt operative pain it will be assessed 2 hourly till 8 hours)
研究者
研究点 (1)
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