Comparison of Quality of Recovery in opioid sparing with Pectoral nerve (Pecs) block vs opioid based anesthesia in patients undergoing Modified radical mastectomy surgery. A randomized controlled trial
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Quality of Recovery (QoR-40) at 24 hours postoperatively: Assessed using the QoR-40 questionnaire, focusing on patient recovery quality
研究概览
简要总结
Opioids are commonly used in anesthesia to manage pain during and after surgery. However, opioid-based anesthesia is associated with potential side effects, including respiratory depression, nausea, constipation, and the risk of dependency. With increasing concerns over these adverse effects, there is growing interest in opioid-free anesthesia approaches. In patients undergoing Modified Radical Mastectomy (MRM), effective postoperative recovery is crucial, as these patients often experience significant postoperative pain. This study aims to investigate whether opioid-sparing anesthesia can provide comparable or superior postoperative recovery outcomes to opioid-based anesthesia in MRM patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- Female
入选标准
- •American society of anaesthesiologist (ASA) class I and class II Age group 18 to 75.
排除标准
- •Known metastasis with the exception axillary lymph nodes.
- •Refusal of the patient to participate in the study History of chronic opioid use Inability to understand the use of patient controlled analgesia (PCA) device.
结局指标
主要结局
Quality of Recovery (QoR-40) at 24 hours postoperatively: Assessed using the QoR-40 questionnaire, focusing on patient recovery quality
时间窗: 24 hours
次要结局
- Opioid consumption: Total opioid consumption (measured in morphine milligram equivalents) within the first 24 hours postoperatively.
研究者
Amit Gupta
AIIMS Patna