Association Between a Biological Pattern of Dysregulation of the HPA Axis and Mental Disorders in Children Exposed to Early Life Stress
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 8
- 试验地点
- 2
- 主要终点
- Mini Kid II : Mini International Neuropsychiatric Interview
研究概览
简要总结
The purpose of this study is to demonstrate an association between a biological pattern of dysregulation of the HPA axis and mental disorders in children exposed to early life stress.
详细描述
The purpose of this study is to demonstrate an association between a biological pattern of dysregulation of the HPA axis and mental disorders in children exposed to early life stress.
Cortisol secretion lead to define two groups : pathologic versus normal cortisol secretion.
Mental disorders is evaluate with Mini-Kids II (a mental health questionary) and lead to define two groups : mental disorders versus no mental disorders
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 8 Years 至 10 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aged 8 to over 10 years
- •To be entrust to ASE of Finistère in stable environment (the same place of residence since 6 months or more)
- •French speaking
- •Oral consent by children
- •Informed and signed consent by tenured of parent authority
排除标准
- •Don't want to participate
- •To have chronic neurologic or endocrinal pathology or don't have access to verbal language.
研究组 & 干预措施
study with just one arm
All of participants are in this arm. Mini Kid II and CBCL score are administered between day 3 and 7. Moreover, salivary test will be remove to evaluate cortisol secretion, 4 time per day during 2 consecutive days.
Psychologic aftercare will be propose if children have psychologic troubles (results of Mini Kid II)
干预措施: Mini Kid II (Behavioral)
结局指标
主要结局
Mini Kid II : Mini International Neuropsychiatric Interview
时间窗: Day 10 to the study
Standardized questionary administered by a physician. There are 30 pages with 17 subjects like depression, maniac trouble, panic trouble, etc.
次要结局
- BRIEF : Behavrioral Rating Inventory of Executive Function(Day 10 to the study)
- CBCL score : Child Behaviour Check List(Day 10 to the study)