Lung Sonography in Patients With Acute Respiratory Distress Syndrome in Intensive Care Unit
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Non aerated lung area changes
研究概览
简要总结
The purpose of this study is to evaluate the role of lung sonography during different PEEP settings in ICU patients with ARDS.
详细描述
Acute respiratory distress syndrome (ARDS) is a clinical syndrome that often occurs in critically ill patients.
Patients with ARDS invariably require mechanical ventilation to improve oxygen transport. An improvement in oxygenation can be obtained by an increase in positive end-expiratory pressure (PEEP).
In critically ill patients with ARDS, lung imaging is been held by the use of chest radiography and the "gold standard" technique, Computed Tomography (CT).
We designed an observational study in which we included patients under mechanical ventilation admitted in our ICU. In all patients PEEP changes were applied and lung sonography was performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Critically ill patients with ARDS admitted in ICU of Evangelismos Hospital
- •length of stay > 48 hours
排除标准
- •age < 18 years
- •emphysema fractures or skin lesions that do not allow the implementation of lung sonography
- •BMI > 35 kg/m2
- •length of stay < 48 hours
结局指标
主要结局
Non aerated lung area changes
时间窗: 20 min after PEEP trial
次要结局
- Arterial oxygen and carbon dioxide partial pressure(20 min after PEEP trial)
研究者
Serafim Nanas
Professor of Critical Care Medicine
University of Athens