NCT07716774进行中（未招募）不适用
Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Lower Urinary Tract Symptoms
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Lower Urinary Tract Symptoms
研究概览
简要总结
This prospective observational study aims to evaluate the effects of sodium-glucose cotransporter 2 (SGLT-2) inhibitors on lower urinary tract symptoms (LUTS) in patients with type 2 diabetes mellitus. Patients who are newly initiated on SGLT-2 inhibitor therapy as part of routine clinical care will be evaluated at baseline and after one month using a 3-day bladder diary and the Overactive Bladder Questionnaire (OAB-v8). Changes in storage symptoms, including urinary frequency, urgency, nocturia, and urinary incontinence, will be assessed to better characterize the impact of SGLT-2 inhibitor therapy on LUTS.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults (≥18 years of age)
- •Patients with type 2 diabetes mellitus newly initiated on oral SGLT-2 inhibitor therapy
排除标准
- •Age <18 years
- •Patients with insulin-dependent diabetes mellitus (IDDM)
- •Patients with diabetes-related complications (e.g., diabetic nephropathy, retinopathy, or vasculopathy)
- •Patients receiving anticholinergic or α-blocker therapy for lower urinary tract symptoms (LUTS)
- •History of urinary incontinence surgery (including any surgical procedure involving the urethral sphincter, bladder neck, pelvic floor, or pelvic nerves)
- •Patients with urinary tract infection (UTI)
结局指标
主要结局
Lower Urinary Tract Symptoms
时间窗: one month
次要结局
未报告次要终点
研究者
Tarik Emre Sener
Associated Professor
Marmara University
研究点 (1)
Loading locations...
相似试验
已完成
2 期
Effect of Sodium Glucose Co-transporter 2 (SGLT2) inhibitor on reducing atypical antipsychotics-induced weight gain in schizophrenia spectrum disorder – A Randomized Controlled TrialChiCTR2400089293Not applicable; there is no funding
已完成
1 期
Effect Of Sodium Glucose Co-Transporter-2 (SGLT-2) Inhibitors on Body Mass Index After 3 Months of Use in Diabetic PatientsNCT07367555Ariba Shafiq360
已完成
不适用
Sodium Glucose Co-Transporter 2 Inhibitors on Estimated Glomerular Filtration Rate in Diabetic Versus Non-Diabetic Chronic Kidney Disease PatientsDiabetesChronic Kidney DiseaseNCT07302464Ain Shams University60
已完成
3 期
SGLT2 Inhibitors in Non-Diabetic CKD: Effects on Vascular Calcification and AnemiaChronic Kidney DiseaseAnemiaNCT07344922Mansoura University100
已完成
2 期
SGLT2 Adjunct in T1DNephropathy, DiabeticType 1 DiabetesNCT07591077Ain Shams University86