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临床试验/NCT07809321
NCT07809321Enrolling By Invitation不适用

Influence of Beta-Alanine Supplementation on Neuromuscular and Cardiovascular Performance in Female Rugby Players

Universidad Pontificia Comillas1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年9月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
Enrolling By Invitation
入组人数
30
试验地点
1
主要终点
Bronco Test (Cardiovascular Test)

研究概览

简要总结

This study will examine the effects of beta-alanine supplementation on physical performance in female rugby players, who will ingest 4.8 grams/day over a four-week period. The research will evaluate both cardiovascular and neuromuscular outcomes, with cardiovascular performance assessed using the Bronco Test (a field-based measure of endurance and repeated high-intensity running ability) and neuromuscular performance (e.g.vertical jump capacity).

详细描述

This study will examine the effects of beta-alanine supplementation on physical performance in female rugby players, who will ingest 4.8 grams/day over a four-week period. Beta-alanine is a dietary supplement known to increase muscle carnosine levels, which may enhance buffering capacity and delay fatigue during high-intensity exercise. The research will evaluate both cardiovascular and neuromuscular outcomes, providing a comprehensive assessment of performance adaptations relevant to rugby. Cardiovascular performance will be assessed using the Bronco Test, a validated field-based measure of endurance and the ability to perform repeated high-intensity running efforts. Neuromuscular performance will be evaluated through measures of upper and lower-body strength /power output. Additionally, the study aims to explore whether beta-alanine supplementation can improve the ability to sustain high-intensity actions and overall physical readiness in female team-sport athletes.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Triple (Participant, Care Provider, Investigator)

盲法说明

An independent researcher who will not be involved in the implementation of the study, data collection, or analysis will be responsible for the allocation concealment and preparation of the supplementation (beta-alanine and placebo). This individual will ensure proper blinding of the interventions so that participants and study personnel involved in outcome assessment remain unaware of group assignments.

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Rugby participants with at least three years of professional experience.

排除标准

  • Suffering from any chronic pathology or an injury in the month prior to the investigation.
  • Intolerance to beta-alanine supplementation
  • Participants aged outside the range of 18 to 40 years.

研究组 & 干预措施

Beta-alanine supplementation

Experimental

Participants assigned to the experimental group will receive beta-alanine supplementation (CROWN Sport Nutrition, La Rioja, España) at a dose of 4.8 grams per day for a period of four weeks . The supplement will be administered in divided doses throughout the day to enhance absorption and minimize potential side effects such as paresthesia

干预措施: Placebo Comparator (Dietary Supplement)

Dietary Supplement: Placebo Comparator

Placebo Comparator

Description: Placebo group will receive 4.8 grams per day of placebo, containing fructose (3000 mg) and excipients (1800 mg) such as cellulose, calcium phosphate, silicon dioxide, and magnesium stearate. Both supplements will be matched in appearance and dosing schedule to ensure proper blinding. Compliance with the supplementation protocol will be monitored throughout the intervention period.

干预措施: Placebo Comparator (Dietary Supplement)

Beta-alanine supplementation

Experimental

Participants assigned to the experimental group will receive beta-alanine supplementation (CROWN Sport Nutrition, La Rioja, España) at a dose of 4.8 grams per day for a period of four weeks . The supplement will be administered in divided doses throughout the day to enhance absorption and minimize potential side effects such as paresthesia

干预措施: Beta-Alanine (Dietary Supplement)

Dietary Supplement: Placebo Comparator

Placebo Comparator

Description: Placebo group will receive 4.8 grams per day of placebo, containing fructose (3000 mg) and excipients (1800 mg) such as cellulose, calcium phosphate, silicon dioxide, and magnesium stearate. Both supplements will be matched in appearance and dosing schedule to ensure proper blinding. Compliance with the supplementation protocol will be monitored throughout the intervention period.

干预措施: Beta-Alanine (Dietary Supplement)

结局指标

主要结局

Bronco Test (Cardiovascular Test)

时间窗: Before and after the intervention period, which lasted four weeks.

The Bronco Test will be used to assess cardiovascular fitness and the ability to perform repeated high-intensity running efforts. This field-based test consists of continuous shuttle running over increasing distances (typically 20, 40, and 60 meters) repeated multiple times without rest, totaling 1,200 meters. Participants are required to complete the test as quickly as possible, with total time recorded as the main performance outcome. The Bronco Test is widely used in team sports such as rugby due to its strong ecological validity, as it reflects the intermittent and high-intensity nature of match play. Improvements in completion time are indicative of enhanced aerobic capacity, speed endurance, and overall cardiovascular performance.

Repeated sprint ability capacity

时间窗: Before and after the intervention period, which lasted four weeks.

Repeated-sprint ability will be assesed using a 6 × 30 m repeated-sprint test, from which two indices were derived: total sprint time and percent sprint decrement. Total sprint time was calculated as the sum of the six individual sprint times, expressed in seconds, and represents overall sprint performance across repeated efforts. The percent sprint decrement was used as an indicator of fatigue, reflecting the decline in performance across successive sprints.

次要结局

  • Isometric handgrip strength(Before and after the intervention period, which lasted four weeks.)
  • Vertical jump capacity (countermovement jump)(Before and after the intervention period, which lasted four weeks.)
  • Modified agility T-test(Before and after the intervention period, which lasted four weeks.)
  • Rate of perceived exertion (RPE)(Before and after the intervention period, which lasted four weeks.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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