NCT04994548已完成不适用
Endoscopic Resection of Early Esophageal Tumors in the Context of Cirrhosis or Portal Hypertension: a Multicenter Observational Study
Central Hospital, Nancy, France0 个研究点目标入组 112 人开始时间: 2005年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 112
- 主要终点
- technical success of early esophageal cancer resection
研究概览
简要总结
Cirrhotic patients may be at high risk for esophageal cancer. Endoscopic resection is the standard treatment for superficial tumors. However, cirrhosis might be associated with upper gastrointestinal bleeding, particularly in case of portal hypertension or coagulopathy. This study aims to assess safety, efficacy and methods to prevent potential complications in cirrhosis or portal hypertension context for esophageal endoscopic resection.
This retrospective multicentric French-Belgian study includes all consecutive patients with cirrhosis or portal hypertension who underwent esophageal endoscopic resection from January 2005 to 2021.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •older than 18 years with cirrhosis or portal hypertension who underwent endoscopic resection of an early esophageal tumor
排除标准
- •younger than 18
结局指标
主要结局
technical success of early esophageal cancer resection
时间窗: baseline
defined by a complete macroscopic resection
次要结局
- preemptive methods to the risk of bleeding(baseline)
- morbidity post procedure (delayed bleeding, infection, esophageal stenosis, 30-days related liver decompensation, 30-days related mortality)(up to 4 weeks)
- adverse events per procedure (immediate bleeding, perforation)(baseline)
- Potential risk factors for adverse events(baseline)
研究者
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