A Randomized Open Label Controlled Clinical Study to Compare the Efficacy of Rasanjanadya Aschyotana and Olopatadine 0.1% Eye Drops in the Management of Kaphaja Abhishyanda (Simple Allergic Conjunctivitis)

Kaphaja Abhishayanda is characterized by Ushnaabhinanda (Want of warmth), Guruta (heaviness of lids), Akhshishopha (swelling of eyes), Kandu (itching), Updeha (stickiness in eyes), Atisitata (Excessive coldness), Sravamuhurpichila (recurrent excessive slimy discharge from eye); so, on the basis of signs and symptoms Kaphaja Abhishyanda can be correlated with Simple Allergic Conjunctivitis. Simple Allergic Conjunctivitis, is a type-1 immediate hypersensitivity reaction mediated by IgE and subsequent mast cell activation, following exposure of ocular surface to airborne allergens.Ayurveda offers an alternative and holistic approach to manage such conditions using herbal formulations that aim at correcting the doshic imbalance while providing symptomatic relief. Rasanjanadya Aschyotana, an Ayurvedic eye drop formulation comprising ingredients like Rasanjana, Haridra, and Madhu is described in classical texts for Kaphaja Abhishyanda*.*This study is designed to evaluate and compare the therapeutic efficacy of Rasanjanadya Aschyotana with that of Olopatadine 0.1% eye drops (Dual action antihistamine and mast cell stabilizer) in patients suffering from Kaphaja Abhishyanda (Simple Allergic Conjunctivitis). By employing a randomized open-label controlled clinical trial design, this research aims to generate scientific evidence for the effectiveness of Rasanjanadya Aschyotana, potentially establishing it as a viable, natural alternative to modern pharmacotherapy.