Leptospirosis Care Bundle Study: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 300
- 试验地点
- 2
- 主要终点
- Number of Participants with Reduce AKI in 72 hours
研究概览
简要总结
So in management of Leptospirosis patients There really is no another approach to treatment. The importance of the problem was acknowledged by the researchers. As a result, this study was performed in order to The Leptospirosis Care Bundle has been used, and has been proved that its use can reduce the risk of acute renal failure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age > 18 years
- •Suspicious Leptospirosis including body temperature > 38 celcius, Severe myalgia, and exposure to reservoir hospital of flood water.
- •Calf muscle tenderness
- •Conjunctival suffusion
- •Anuria or oliguria and/or proteinuria
- •Hemorrhagic manifestations (pulmonary and intestine)
- •Meningeal irritation
- •Nausea, vomiting, abdominal pain, diarrhea.
- •Admitted in hospital
排除标准
- •other infectious disease
- •pregnancy
结局指标
主要结局
Number of Participants with Reduce AKI in 72 hours
时间窗: 72 hours
To see if using care bundle for leptospirosis patients can improve reduce the incidence of acute renal failure in the first 72 hours of being admitted to hospital.It classified AKI into three categories (risk, injury, and failure) according to the status of serum creatinine (SCr) and urine output (UO) by AKIN/KDIGO
次要结局
未报告次要终点
研究者
Nattachai Srisawat ,M.D.
Assoc. Prof. Dr.Nattachai Srisawat
Chulalongkorn University