ChiCTR2500102879尚未招募Unknown
Taurine Or Placebo for Healthcare Workers: the TOP Healthcare workers' Bayesian Optimized Phase II randomised-controlled trial
Department internal funding3 个研究点 分布在 1 个国家开始时间: 2025年7月1日最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 试验地点
- 3
- 主要终点
- HbA1c
研究概览
简要总结
To assess whether oral taurine supplementation will improve metabolic health of healthcare workers.
研究设计
- 研究类型
- Interventional
- 主要目的
- 随机平行对照
- 盲法
- Everyone will be blinded to the study capsules - maybe except the company that manufactures the study capsules in Western Australia. Bottle will be labelled as A or B (with certain serial study number).
入排标准
- 性别
- All
入选标准
- •Healthcare related workers who can read and understand English or Chinese translated version of the study questionnaires will be invited to participate including doctors, nurses, physiotherapists, dietitians, or research-related workers at the New Territories East Cluster Hospitals
排除标准
- •(a)Are taking taurine prior to enrolment,
- •(b) Have chronic renal disease (eGFR<30ml/min: as taurine can accumulate in renal failure)
- •(c) Insulin-dependent diabetes mellitus
- •(d) A bleeding disorder (e.g. platelet count < 100x10^9/L or treated with dual antiplatelet agents: as taurine has potential antiplatelet activity in vitro)
- •(e) Received active chemo/immunotherapy < 30 days before enrolment or likely to receive such treatment during the study
- •(f) Pregnant or planning to become pregnant
研究组 & 干预措施
Treatment group
Placebo group
结局指标
主要结局
HbA1c
时间窗: At 6 month follow-up from baseline
Methylglyoxal level
时间窗: At 6 month follow-up from baseline
Plasma taurine level
时间窗: At 6 month follow-up from baseline
次要结局
- LDL and triglyceride levels(At 6 month follow-up from baseline)
- PhenoAge(At 6 month follow-up from baseline)
- Body weight(At 6 month follow-up from baseline)
- IPAQ(At 6 month follow-up from baseline)
- Blood pressure(At 6 month follow-up from baseline)
- Center for Epidemiologic Studies Depression Scale(At 6 month follow-up from baseline)
- AGEs index(At 6 month follow-up from baseline)
- Differences in gut microbiome(At 6 month follow-up from baseline)
- Albumin(At 6 month follow-up from baseline)
- Creatinine(At 6 month follow-up from baseline)
- C-reactive protein(At 6 month follow-up from baseline)
- Complete blood count(At 6 month follow-up from baseline)
- Alkaline phsphatase(At 6 month follow-up from baseline)
研究者
研究点 (3)
Loading locations...
相似试验
尚未招募
2 期
A Multicenter Clinical Trial Evaluating the Efficacy and Safety of Taurine as an Adjunctive Therapy in Multiple SclerosisNCT07263607Sichuan Academy of Medical Sciences80
已完成
不适用
Low-Dose Caffeine and Taurine Effects on PerformanceNCT07466654Ankara University32
招募中
不适用
Does Taurine Supplementation Improve Vascular Function and Orthostatic Responses in Long COVID?NCT07312409York University30
尚未招募
不适用
Effect of Taurine Supplementation on Physical Performance in Kabaddi PlayersCTRI/2026/02/0103087College of Physiotherapy PGIMS Rohtak India20
招募中
不适用
A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant MedicationsNCT07380412Outliers, Inc.90