Adaptive Text Messaging Reminders Combined With Non-monetary Incentives to Improve Adherence to Antiretroviral Treatment Among Adolescents Living With HIV in Ethiopia: a Hybrid Effectiveness-implementation Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 327
- 试验地点
- 1
- 主要终点
- Adaptive text messaging reminders combined with non-monetary incentives to improve sustained adherence to antiretroviral treatment among adolescents in Ethiopia: a hybrid effectiveness-implementation trial
研究概览
简要总结
Many adolescents living with HIV have difficulty taking their medicine on time, which can make it less effective and affect their health. This study will test whether sending reminder text messages, combined with small rewards like school supplies, hygiene kits, or sports items, can help adolescents take their HIV medicine regularly and stay in care. Each adolescent will choose a daily habit or routine to link to their medication. We will compare two groups receiving messages and rewards to a group receiving standard care to see which approach works best. We will also ask participants about their experience with the messages and rewards. The aim is to find a simple and effective way to help adolescents living with HIV stay healthy and in care.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 15 Years 至 19 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Consenting adolescents aged 15 to 19 who have been on ART for at least a year and want to continue treatment at the selected facility during the trial period are eligible.
排除标准
- •Participants outside of the specified age range.
研究组 & 干预措施
Control (standard care)
Non-adaptive reminder text messaging combined with non-monetary incentives
干预措施: Adaptive interventions (Behavioral)
Non-adaptive reminder text messaging combined with non-monetary incentives
干预措施: The control arm (Behavioral)
Adaptive text messaging
干预措施: Non-adaptive reminder text messaging (Behavioral)
Adaptive text messaging
干预措施: The control arm (Behavioral)
结局指标
主要结局
Adaptive text messaging reminders combined with non-monetary incentives to improve sustained adherence to antiretroviral treatment among adolescents in Ethiopia: a hybrid effectiveness-implementation trial
时间窗: 12 months
ART adherence will be measured using a multi-method composite adherence assessment tool based on previously validated measures, including self-reported adherence, pill count (PC), and retention in care (missed appointments). Self-reported adherence will be assessed through four validated yes/no questions addressing difficulties remembering medication, intentional discontinuation when feeling better or worse, and missed doses over the preceding four days. Participants will also rate their adherence over the past 30 days using a visual analogue scale (VAS) ranging from 0 (no adherence) to 10 (perfect adherence). Each adherence component will be dichotomized using established thresholds (≥95% adherence for self-report, pill count, and VAS; no missed appointments for retention in care) and assigned a score of 1 (adherent) or 0 (non-adherent). Component scores will be summed to generate a composite adherence index ranging from 0 to 3, which will be reported as a single adherence measure ca
次要结局
- Implementation Outcomes of Adaptive SMS Reminders with Incentives for Adolescents Living with HIV(3-12 months)
- Effect of Adaptive SMS and Incentives on 12-Month Viral Suppression in Adolescents with HIV(12 months)
- Cost-Effectiveness and Cost-Utility of Adaptive SMS Reminders with Non-Monetary Incentives for Improving ART Adherence Among Adolescents with HIV(12 months)
研究者
Abayneh Tunje Tanga
Adaptive text messaging reminders combined with non-monetary incentives to improve adherence to antiretroviral treatment among adolescents in Ethiopia: a hybrid effectiveness-implementation trial
Arba Minch University