NCT02077400已完成不适用
The Use of Prophylactic Antibiotic in Treatment of Fingertip Amputation: A Randomized Prospective Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- infection rate
研究概览
简要总结
Fingertip amputation is a common injury. Considerable controversy exists as to whether prophylactic antibiotics are necessary for this injury. The investigators goal was to compare the rate of infections among subgroups with and without prophylactic antibiotic treatment. The study hypothesis was that infection rates were similar in the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •fingertip amputation with bone exposed
排除标准
- •under the age of 18 years
- •if the patient had diabetes
- •oncological disorder
- •immune deficiency
- •bleeding disorder
- •used steroids regularly
- •presented with a grossly contaminated wound or other injury requiring antibiotic treatment
- •were currently taking antibiotics, or had a previous allergic reaction to cephalosporins.
研究组 & 干预措施
Cephazolin
Active Comparator
cefazoline
干预措施: Cephazolin (Drug)
结局指标
主要结局
infection rate
时间窗: 1 month
次要结局
未报告次要终点
研究者
guy rubin
Dr.
HaEmek Medical Center, Israel
研究点 (1)
Loading locations...
相似试验
终止
不适用
Antibiotic Prophylaxis for Simple Hand LacerationsSimple Hand LacerationsNCT01155154State University of New York - Downstate Medical Center73
已完成
4 期
Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor TendonHand LacerationTendon InvolvedClean LacerationNo Bone InvolvedNCT01899781HaEmek Medical Center, Israel24
已完成
不适用
Antibiotic Prophylaxis in Orthopaedic TraumatologyFractures, ClosedWounds and InjuriesNCT00610987University of Missouri-Columbia178
招募中
3 期
Antibioprophylaxis for Excision-graft Surgery in Burn Patient (A2B-TRIAL)Burns SurgeryNCT04292054Assistance Publique - Hôpitaux de Paris506
已完成
4 期
Antibiotic prophylaxis and prevention of wound infections following implant removal after foot, ankle and lower leg fracturespostoperative wound infection100173221004078510005944NL-OMON44330Academisch Medisch Centrum500