跳至主要内容
临床试验/NCT03429712
NCT03429712终止不适用

Patient- and Task-specific Radiation Dose Optimization for Pediatric Abdominopelvic CT Applications

Duke University1 个研究点 分布在 1 个国家目标入组 19 人开始时间: 2018年9月15日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
终止
发起方
入组人数
19
试验地点
1
主要终点
Image Noise

研究概览

简要总结

Radiation dose reduction has been a primary driver of technology development in multi-detector computed tomography (MDCT). The optimization of radiation dose for patient and task specific computed tomography (CT) applications continues to be an ongoing challenge, especially in pediatric patients where the desire to reduce radiation dose to lowest possible levels leads to both positive and negative effects. A novel research tool on the Siemens dual source (Flash® and Force ®) CT scanners allows one to assess multiple tube current levels from a single CT acquisition without incurring additional dose to the patient. Tube current is a primary contributor to radiation dose and image noise, which are inversely related. This is achieved by independently adjusting the current of each tube, while maintaining same kV in each x-ray tube. Moreover, Duke's medical physics team has developed a method based on mathematical expressions that allows the creation of incremental dose levels from the acquired image data sets. This innovative and powerful tool can be used to compare diagnostic accuracy, detectability, and many more relevant clinical features amongst multiple tube current levels with the attainment of a single CT acquisition.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
— 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

研究组 & 干预措施

Dose Split CT

Experimental

干预措施: Dual-source multi-detector computed tomography (DSSE) (Device)

结局指标

主要结局

Image Noise

时间窗: Up to 5 minutes

次要结局

未报告次要终点

研究者

发起方
Duke University
申办方类型
Other
责任方
Sponsor

研究点 (1)

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