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临床试验/NCT03893123
NCT03893123Unknown不适用

Prostate Cancer Risk in Firefighters: Its Association to Qualitative and Quantitative Indicators of Exposure

Oslo University Hospital1 个研究点 分布在 1 个国家目标入组 4,500 人开始时间: 2018年1月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
4,500
试验地点
1
主要终点
Incidence of prostate cancer

研究概览

简要总结

Firefighters have been shown to be at increased risk for various types of cancer, including prostate cancer. This study will try to explore possible reasons for this increase in risk. A study group at the Cancer Registry of Norway is creating a cohort of Norwegian firemen employed from 1960 onwards. A job exposure matrix (JEM) is also being constructed, examining different types of exposure to potentially cancer-inducing agents and activities, and how these have changed historically. Examples include exposure to fire-smoke, shiftwork, diesel exhaust and regular health check-ups. By linking the cohort with data from the Cancer Registry of Norway and the JEM the investigators can examine which exposure assessments, if any, are related to an increased risk of prostate cancer.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
Male
接受健康志愿者

入选标准

  • Work as firefighter as recorded by the participating fire stations

排除标准

  • Any other occupation, including chimney sweepers

结局指标

主要结局

Incidence of prostate cancer

时间窗: From January 1st 1960 until December 31st 2018

As reported to the Cancer Registry of Norway

次要结局

未报告次要终点

研究者

发起方
Oslo University Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Jarle Jakobsen

PhD-student

Norwegian Institute of Public Health

研究点 (1)

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