NCT01684280已完成不适用
Searching for the Most Influential Obesity-related Diabetic Genes and Exploring the Expression Profiles of Those Genes in Taiwanese Undergoing Weight Loss
Sung Ling Yeh1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2010年6月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- MicroRNA expression in abdominal omental adipose tissues
研究概览
简要总结
To investigate:
- Associations between miRNA and insulin signaling-related gene expressions in abdominal adipose tissues in obese subjects.
- Differences in miRNAs expressed by intrabdominal omental adipose tissues between genders.
详细描述
Compared the differences in microRNA expressions of abdominal adipose tissue in morbid obese male and female subjects to elucidate the possible regulatory role of microRNA in insulin signaling-related gene expression levels and its association with biochemical markers. We hope to find a miRNA that can be used to predict the syndrome associated with obesity.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 19 Years 至 63 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Morbid obesity,BMIs> 40 kg/m2
- •Subjects who underwent bariatric surgery
排除标准
- •Obese subjects with complicated metabolic disorders
- •Thyroid disease
结局指标
主要结局
MicroRNA expression in abdominal omental adipose tissues
时间窗: up to 28 weeks
MicroRNA-125a-3p expression in abdominal omental adipose tissues is associated with insulin signaling-related gene expression levels in morbid obesity
次要结局
未报告次要终点
研究者
Sung Ling Yeh
professor
Taipei Medical University Hospital
研究点 (1)
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