ChiCTR-TRC-09000739已完成Unknown
Combination of Aprepitant and Dexamethasone to Prevent Postoperative Nausea and Vomiting
Departmental1 个研究点 分布在 1 个国家目标入组 320 人开始时间: 2006年2月1日最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 已完成
- 发起方
- 入组人数
- 320
- 试验地点
- 1
- 主要终点
- Complete response (no vomiting, no nausea, no rescue antiemetic)
研究概览
简要总结
Combination of Aprepitant and Dexamethasone to Prevent Postoperative Nausea and Vomiting
研究设计
- 研究类型
- Interventional
- 主要目的
- 随机平行对照
- 盲法
- Double
入排标准
- 年龄范围
- 18 至 65（—）
- 性别
- Male
入选标准
- •All women (age 18-65 years) undergoing open gynecologic surgery will be eligible
排除标准
- •(1) Patients had preexisting nausea or vomiting;
- •(2) Patients had received opioids or drugs with known antiemetic properties in the 24 hours before surgery;
- •(3) Pregnant patients;
- •(4) Patients with history of esophageal reflux, opioid or alcohol abuse.
研究组 & 干预措施
Two groups
Aprepitant Immediately before induction of anesthesia Dexamethasone and a combination of Aprepitant and Dexamethasone
结局指标
主要结局
Complete response (no vomiting, no nausea, no rescue antiemetic)
次要结局
- QoR,FLIE questionnaire, Pain and nausea score
研究者
研究点 (1)
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