NCT05340218已完成不适用
"Análisis Longitudinal Del Habla y Seguimiento a Corto Plazo de Las Facultades Cognitivas de Personas Mediante Una Serie de Pruebas: Lista de Palabras CERAD, Repite Los dígitos en Orden Inverso, TMTA-B, Prueba Del Reloj, Fluidez fonémica, comprensión Verbal Relaciones semánticas, y semánticas Alternas".
Accexible1 个研究点 分布在 1 个国家目标入组 196 人开始时间: 2019年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 196
- 试验地点
- 1
- 主要终点
- Pre-post variability of normal, MCI and dementia at both points of the study.
研究概览
简要总结
Validate speech analysis AI models:
- To contrast the accuracy of acceXible's platform as a screening tool in the detection of people with cognitive impairment and mild dementia.
- To evaluate the correlation between automatically analyzed linguistic variables and a combination of standard measures of cognition.
- To assess short-term variability in language ability among older adults, and to assess which aspects of language vary during the study period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult patients 55+ years of age with suspected MCI or diagnosis of dementia and obtains a score greater than 20 on the MMSE.
- •Patients must have agreed to participate in the study and have voluntarily signed the informed consent.
- •(Healthy) Participants without a diagnosis neurological, or psychiatric disorders. Or taking medication that can affect cognitive abilities.
排除标准
- •To have received a diagnosis of a significant psychiatric disorder or other cognitive impairment not due to neurodegeneration.
- •To have significant vision problems that would affect the ability to perceive visual stimuli.
- •To have significant hearing problems that would affect the ability to understand verbal cues.
结局指标
主要结局
Pre-post variability of normal, MCI and dementia at both points of the study.
时间窗: Change from the baseline cognitive function at 9 months.
Through standard deviation of normal subjects, MCI and dementia, variations in language are measured by considering MMSE scores and the most significant variables of accexible's tests (image description test, phonetic verbal fluency test and semantic verbal fluency test).
次要结局
- Correlation between cognitive tests and language variables obtained by the platform.(Every 6 to 9 months)
研究者
研究点 (1)
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