"Fight-or-flight" Versus "Tend-and-befriend" Response to Behavioral and Pharmacological Interventions in Patients With Borderline Personality Disorder - Part I
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 196
- 试验地点
- 1
- 主要终点
- empathy
研究概览
简要总结
The investigators will examine whether perceived social exclusion provoke a reduction in prosocial behavior in BPD patients.
详细描述
The investigators will examine whether perceived social exclusion provoke a reduction in prosocial behavior, such as empathy, in BPD patients and whether this "fight-or-flight" pattern is also seen in other relevant aspects of social behavior, such as sharing and punishment behavior. To induce social exclusion all participants will play cyberball, either the exclusion condition or the (over)inclusion condition before testing
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •female patients with BPD and healthy control women, matched for age, body mass index, and education
排除标准
- •physical illness
研究组 & 干预措施
exclusion BPD
cyberball exclusion condition - BPD patients
干预措施: inclusion condition (Behavioral)
over-inclusion BPD
cyberball over-inclusion condition - BPD patients
干预措施: inclusion condition (Behavioral)
exclusion healthy controls
cyberball exclusion condition - healthy controls
干预措施: inclusion condition (Behavioral)
over-inclusion healthy controls
cyberball over-inclusion condition - healthy controls
干预措施: inclusion condition (Behavioral)
结局指标
主要结局
empathy
时间窗: 30 minutes after cyberball
Multifaceted Empathy Test
次要结局
- sharing behavior: amount of monetary units (max 30) shared with co-player(directly after cyberball)
研究者
Katja Wingenfeld
Principal Investigator
Charite University, Berlin, Germany