The effect of chitosan supplementation on some appetite regulating hormones, intestinal microbiota, anthropometric indices and blood sugar and lipid control indices in overweight and obese adolescents

Iran University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2021年6月21日

试验速览

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•Willingness to cooperate
•Overweight and obese girls and boys 10 to 18 years old with Z score body mass index higher than 1 and less than 3 for age and sex

•Use of probiotic or prebiotic or synbiotic supplements for the past three months or any foods fortified with these supplements • Take any antibiotics 3 months before the study • Have type 1 or 2 diabetes, cardiovascular disease or hepatic, gastrointestinal (Celiac, IBD or IBS) or renal disorders or all metabolic disorders including PKU, MSUD, urea cycle disorders or .. • History of gastrointestinal surgery • Taking drugs or supplements that affect appetite, weight or metabolism at least three months before the study (such as medications that affect carbohydrate, protein or fat metabolism, and medications that reduce or increase appetite or food intake, including herbal supplements) • Have any weight loss diet or any program heavy exercise in the last 6 months • Pregnancy and lactation • Smoking (more than one cigarette per week or more than 200 cigarettes in a lifetime) • Having any allergies to chitosan or shrimp • • 1- Having any acute illness • 2- Occurrence of any accident that affects a person's health • 3- Taking antibiotics while studying • 4- Low acceptance rate more than 80% • 5- Not following the intervention • 6- Immigration • 7- Leaving the study based on the personal desire of the participants or their parents

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