Comparison Between Analog Neurocognitive Tests Conducted by a Trained Test Leader Versus Self-administered Digital Tests: a Protocol for an Equivalence Study

Study design: Randomized crossover design including qualitative interviews of the test procedures.

Participants:The participants are planned to be healthy controls (n=50) comprising men and women of >60 years of age. The number of participants is guided by an earlier cross over studies with older adults assessing cognition digitally and analogy The participants will self-report if they meet any of the exclusion criteria: inability to read and speak Swedish, suffering from a nervous system disease, severe psychiatric disorder, alcoholism, drug dependance and severe visual or auditory disorder.

Cognitive tests Verbal episodic memory ISPOCD: The Visual Verbal Learning Test with 15 words that are individually presented over a series of 3 consecutive presentations. Each word is presented visually for 2 seconds. The participant is asked to recall as many words as possible after each trial as well as after 20 min without further presentation of word, i.e. delayed recall.

Mindmore: CERAD is a 10-word verbal learning test with 3 learning trials, a recall trial after ~7 min and a recognition trial. Compared to RAVLT this test is shorter, but also a little less sensitive. Words are read and visually presented in writing to the patient and the patient replies in speech.

Executive, visuospatial (assess processing speed) ISPOCD: The Concept Shifting Test is a trail-making test where the participant is required to alternate between letters and digits. Each part consists of 16 circles on a paper. In part A, the circles are numbered from 1 to 16. The test person is instructed to draw a short over each number in ascending order from 1 to 16, as rapidly as possible. Part B consists of letters from A-P. Part C consists of 8 digits and 8 letters to be paired and the test person is instructed to draw a short over each and letter order (1-A, 2-B, 3-C and so on).