Manganese, Possible Factor of Higher Mortality in Women With Encephalopathy
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- Clinical Evolution
研究概览
简要总结
Objective:
Report manganese serum levels and mortality in encephalopathic patients.
Patients and participants:
Consecutive patients aged > 18 years, with hepatic encephalopathy and informed consent signed by their families.
Interventions:
Patients' clinical characteristics as well as biochemical tests of renal function, hemoglobin, glucose and albumin levels were obtained as well as a blood sample to analyze manganese levels with a graphite furnace atomic absorption spectrometer.
Hypothesis:
There is a difference in the manganese levels between male and female patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Consecutive patients aged > 18 years
- •With hepatic encephalopathy
- •Informed consent signed by their families
排除标准
- •Portal bypass surgery
- •Cancer of any localization
- •Known malignancy and other severe diseases which shorten life expectancy < 6 months
- •Psychiatric illness
结局指标
主要结局
Clinical Evolution
时间窗: six months
Number of participants who died versus those who remained alive after 6 months of follow up since the first entrance at the Emergency Room
次要结局
- Manganese Levels(Up to six months we followed the recruited patients to determine who were still alive)
