Treatment of Internal Inflammatory Root Resorption Using Injectable PRF Revascularization Technique: A Clinical Study With Cone Beam Computed Tomography Evaluation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- change in volumetric size of internal root resorption lesions
研究概览
简要总结
Currently Endodontics looks forward for regeneration rather than repair. Regenerative endodontic therapy was limited to pulp revascularization of necrotic pulp in immature teeth , followed by mature teeth. Recently pulp revascularization technique by induction of blood clot was applied in the treatment of inflammatory root resorption. So far, no clinical study for management of teeth with inflammatory internal root resorption by using injectable PRF revascularization has been described in the literature. Thus, this is the first clinical attempt to manage inflammatory root resorption in necrotic incisor teeth using injectable PRF regenerative approach.
详细描述
13 teeth in a total of 10 patients with inflammatory root resorption will be treated using revascualrization technique, iPRF will be prepared and unjected in the canal after previous canal disinfection with calcium hydroxide for 2-4 weeks. cBCT will be taken preoperative and 12 month follow up period, also clinical and radiographic follow uo will be considered every 3 months for 1 year.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 13 Years 至 30 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients 13-30 years old
- •no sex predilection
- •medically free
- •Suffering from internal inflammatory root resorption in permanent anterior mature teeth
- •associated with or without periapical radiolucency
- •no or grade I tooth mobility, and a pocket depth <3 mm
排除标准
- •Medically medically compromised patients
结局指标
主要结局
change in volumetric size of internal root resorption lesions
时间窗: 12 months
Measuring volumetric dimensions of resorption lesion pre and postoperatively using CBCT
次要结局
- change in volumetric size of periapical lesions(12 months)
研究者
Mohamed Nageh
Lecturer of Endodontics
Fayoum University