The Effects of Vitamin D2 Supplement During Pregnancy on Postpartum Maternal and Fetal Vitamin D Levels: the Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- effect of vitamin D 2 supplementation during pregnancy
研究概览
简要总结
The effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels: the randomized controlled trial
详细描述
Vitamin D structurally similar to steroids. Made from the skin. And metabolism of the liver, kidneys, vitamin D levels in the bloodstream are two types of vitamin D 2 (Ergocalciferol) and vitamin D 3 (Cholecalciferol) Vitamin D regulates calcium and phosphorus levels in the body. Including the accumulation of minerals in the bone. Vitamin D is important in the formation of bones and teeth and the normal growth of children, affects the reabsorption of amino acids in the kidneys, regulates the amount of calcium and phosphorus in the blood Vitamin D deficiency in pregnant affects the mother and baby example high maternal blood pressure during pregnancy, diabetes during pregnancy, increase birth body weight of baby. low calcium seizures Infants, baby have bones and growth disorders. Currently, no vitamin D supplement is used in pregnant women in Thailand who attend antenatal clinics. The researcher has proposed to study the effects of vitamin D supplement during pregnancy on postpartum maternal and fetal vitamin D levels by using vitamin D 20,000IU / week
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Women who have pregnant and ANC at Rajavithi hospital
- •Women who have age at least 18 year
- •Women who have Thai nationality
- •Women who have pregnant of gestational age under 20week
排除标准
- •Women who don't plan of delivered at Rajavithi hospital
- •Women who have complication of pregnancy
- •Woman who delivered before gestational age 37week
- •Women who have abnormal kidney function
- •Woman who have been used anticonvulsant drug or others form of vitamin d
- •Women who have vitamin d allergy
研究组 & 干预措施
Oral calciferol group
Subjects will receive oral calciferol 20,000 iu per week during pregnancy until delivered
干预措施: Calciferol (Drug)
oral placebo group
Subjects will receive oral placebo 1 tab per week during pregnancy until delivered
干预措施: Placebo (Drug)
结局指标
主要结局
effect of vitamin D 2 supplementation during pregnancy
时间窗: within 30 minute after delivered
To study the effect of vitamin D 2 supplementation during pregnancy on postpartum maternal and fetal vitamin D levels effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels
次要结局
- vitamin D levels in maternal blood after vitamin D supplementation(within 30 minute after delivered)
- vitamin D levels in maternal blood during pregnancy(at first time ANC)