A retrospective study on the effects of gene polymorphisms on postoperative pain management in patients undergoing major abdominal surgery - A study on gene polymorphism effects on postoperative pain management

American Society of Human Genetics (ASHG) 57th Annual Meeting Japanese Society of Clinical Neuropsychopharmacology (JSCNP) 19th Annual Meeting / Japanese Society of Neuropsychopharmacology (JSNP) 39th Annual Meeting American Society of Human Genetics (ASHG) 60th Annual Meeting Japanese Society of Clinical Neuropsychopharmacology (JSCNP) 20th Annual Meeting / Japanese Society of Neuropsychopharmacology (JSNP) 40th Annual Meeting Japanese Society of Clinical Neuropsychopharmacology (JSCNP) 22th Annual Meeting / Japanese Society of Neuropsychopharmacology (JSNP) 42th Annual Meeting European Human Genetics Conference 2013 XXIst World Congress of Psychiatric Genetics Method of evaluating drug-sensitivity by analyzing the mu-opioid receptor gene Method of evaluating drug-sensitivity by analyzing the GIRK channel genes Hayashida M, Nagashima M, Satoh Y, Katoh R, Tagami M, Ide S, Kasai S, Nishizawa D, Ogai Y, Hasegawa J, Komatsu H, Sora I, Fukuda K, Koga H, Hanaoka K, Ikeda K. Analgesic requirements after major abdominal surgery are associated with OPRM1 gene polymorphism genotype and haplotype. Pharmacogenomics. 2008 Nov;9(11):1605-16. Nishizawa D, Nagashima M, Katoh R, Satoh Y, Tagami M, Kasai S, Ogai Y, Han W, Hasegawa J, Shimoyama N, Sora I, Hayashida M, Ikeda K. Association between KCNJ6 (GIRK2) gene polymorphisms and postoperative analgesic requirements after major abdominal surgery. PLoS One. 2009 Sep 16;4(9):e7060. Nishizawa D, Fukuda K, Kasai S, Hasegawa J, Aoki Y, Nishi A, Saita N, Koukita Y, Nagashima M, Katoh R, Satoh Y, Tagami M, Higuchi S, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Koga M, Arinami T, Kaneko Y, Hayashida M, Ikeda K. Genome-wide association study identifies a potent locus associated with human opioid sensitivity. Mol Psychiatry. 2014 Jan;19(1):55-62. doi: 10.1038/mp.2012.164. Epub 2012 Nov 27.