跳至主要内容
临床试验/NCT05760495
NCT05760495招募中不适用

Analysis of Oxidative Stress Biomarkers and Their Determinants in ART-experienced PLWH

Fondazione Policlinico Universitario Agostino Gemelli IRCCS1 个研究点 分布在 1 个国家目标入组 543 人开始时间: 2022年9月2日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
543
试验地点
1
主要终点
Assessment of the levels of total oxidant and antioxidant plasma capacity

研究概览

简要总结

The project aims to assess the level of oxidative stress biomarkers in HIV patients on effective antiretroviral treatment in correlation with other therapeutic, clinical, and viro- immunological parameters. The analysis aims to better characterize the patient on treatment through an innovative approach based on two specific tests for complementary assessment of total oxidant and anti-oxidant plasma capacity.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ART-treated PLWH
  • HIV-1 RNA< 50 copies/mL
  • Stable ART therapy (at least 48 weeks)
  • Signature of informed consent for study participation

排除标准

  • 未提供

结局指标

主要结局

Assessment of the levels of total oxidant and antioxidant plasma capacity

时间窗: 1 year

Quantify the levels of total oxidant and antioxidant plasma capacity antioxidant

次要结局

  • Correlation between level of oxidative stress biomarkers and several factors(1 year)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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