A prospective study to determine the occurrence of hypothyroidism following treatment with radiation therapy in patients of head and neck carcinomas and the influencing factors

Dr Suparna Kanti Pal0 个研究点目标入组 80 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1.Adult patients[ more than 18 years of age] with non-metastatic Head & Neck carcinoma, without any intracranial extension, of the following sites-
•a.Nasopharynx
•b.Sinonasal cavity
•c.Oropharynx
•d.Oral cavity
•e.Hypopharynx
•g.CUP [Carcinoma of unknown primary]
•2.Patients receiving radiotherapy( >45 Gy) as part of treatment
•3.Radiation field extending to lower neck , unilateral or bilateral
•4.Performance score- 0 to 2

•11.Known to have hypothyroidism
•a)At the time of screening
•b) The history of hypothyroidism in the past, for which he/she is currently on supplements. [Hypothyroidism was defined as TSH more than the maximum of the normal range, or TSH >4.5 micro IU/ml].
•2.Who has a history of previous exposure to radiation therapy in Head and neck region
•3.Carcinomas with intracranial extension by clinical or radiological examination

发起方

Dr Suparna Kanti Pal