Comparative Evaluation of The Effectiveness of Ozonated Olive Oil and Photodynamic Therapy as an Adjunct to Scaling and Root Planning in Treatment of Patients with Stage II or III Periodontitis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Mean reduction in Probing Pocket Depth (PPD in mm) and gain in Clinical Attachment Level (CAL in mm) at treated sites following intervention (SRP alone vs SRP with Ozonated Olive Oil vs SRP with Photodynamic Therapy)
研究概览
简要总结
This study is a randomized comparative clinical trial evaluating the effectiveness of ozonated olive oil and photodynamic therapy (PDT) as adjuncts to scaling and root planing (SRP) in patients with Stage II and Stage III periodontitis
A total of 60 systemically healthy patients will be divided into three groups
- Group A: SRP alone
- Group B: SRP with ozonated olive oil
- Group C: SRP with photodynamic therapy
Clinical parameters including probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BOP), plaque index (PI), and gingival index (GI) will be recorded at baseline, 1 month, 3 months, and 6 months.
The study aims to determine which adjunctive therapy provides superior clinical improvement in periodontal health, thereby helping to optimize non surgical periodontal treatment protocols.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Age of the patient should be between 20 years to 60 years Systemically healthy patients Patients diagnosed with Aggressive Periodontitis Stage II and III Periodontitis (American Academy of Periodontology and European Federation of Periodontology 2017) Patients having probing pocket depth (PPD) greater than or equal to 5 mm Patients who had not taken antibiotics within 6 months Patients with horizontal bone loss in orthopantogram (OPG) Willingness to comply with the study protocol and follow-up visits.
排除标准
- •Patient who went through scaling in the last 6 months Patient who went through scaling in the last 6 months Stage I Periodontitis (American Academy of Periodontology and European Federation of Periodontology) Lactating or Pregnant females.
- •Patients who are current users of any mouth rinses Patients who have undergone periodontal surgery within the last 6 months Patients using antibiotics or anti inflammatory medications within the last 3 months Patients with systemic diseases that could affect periodontal health (for example diabetes, cardiovascular diseases) Inability to participate & follow up procedures.
结局指标
主要结局
Mean reduction in Probing Pocket Depth (PPD in mm) and gain in Clinical Attachment Level (CAL in mm) at treated sites following intervention (SRP alone vs SRP with Ozonated Olive Oil vs SRP with Photodynamic Therapy)
时间窗: Baseline, 3 months and 6 months
次要结局
- Percentage of sites with Bleeding on Probing (BOP)(Mean Plaque Index (Silness and Löe score))
研究者
Dr Abhisikta Biswal
Kalinga Institute of Dental Sciences, KIIT Deemed to be University