Prevalence of Environmental Enteropathy Among Infants and Children With Growth Faltering
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- Assessment of the prevalence of environmental enteropathy among children with faltering growth.
研究概览
简要总结
The study was conducted on 200 patients with growth faltering on 2 phases. In the first phase the patient received nutritional rehabilitation with polymeric formula for 12 weeks then they were reassessed by anthropometric measurements and those whose weight remained below -2 SD for age and sex on the WHO scores were defined as non responders and entered the second phase. In the second phase Upper Gastrointestinal endoscopy was done and then patients received nutritional rehabilitation with peptide based formula and probiotics then were reassessed after 8 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Months 至 5 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients whose weight below -2 SD for age and sex on the WHO scores.
排除标准
- •Secondary cases of malnutrition or undernutrition.
- •Patients with symptoms of GIT problems as chronic vomiting, chronic or bloody diarrhea, chronic abdominal distension, hematemesis or bleeding per rectum.
- •Patients who can't commit to a follow up visit every two weeks.
结局指标
主要结局
Assessment of the prevalence of environmental enteropathy among children with faltering growth.
时间窗: 12 weeks of nutritional rehabilitation with polymeric formula.
Assess the number of patients whose weight still below -2SD and upper gastrointestinal endoscopy showed the criteria of environmental enteropathy.
次要结局
- Determine the increase in weight of children with growth faltering and environmental enteropathy after nutritional rehabilitation with peptide-based formula.(8 weeks of nutritional rehabilitation with peptide-based formula.)
研究者
Haya Essam Ibrahim
Lecturer of pediatrics
Ain Shams University