The Application of a Mask in Patients With Severe Covid-19 Already Treated With High-flow Nasal Cannula.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Region Skane
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Oxygenation
研究概览
简要总结
Patients with severe hypoxemic respiratory failure due to Covid-19 are often treated with oxygen delivered through a high-flow nasal cannula (HFNC). This is according to guidelines. We have made the clinical observation that oxygenation sometimes improves when a mask (e.g. oxygen mask or inhalation mask) is applied on top of the HFNC. This has quickly become a clinical routine at intermediary care units at our hospital, where patients with HFNC are offered to test the intervention (mask + HFNC) as part of clinical routine.
This study aims to evaluate this new routine in a standardised way.
详细描述
Patients with severe covid-19, treated with HFNC, will be approached for consent. If inclusion critera and no exclusion criteria are fulfilled, baseline measurements will be taken without mask, including arterial blood gas analysis (ABG)
Then a simple oxygen mask will be applied covering nose and mouth, without providing supplemental oxygen. After 30 minutes with mask + HFNC, new measurements will be taken, including ABG.
After 30 minutes, the mask is removed and when steady state occurs, new measurements will be taken, without ABG. Then, the patients could continue using the mask as part of clinical routine
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Verified Covid19 infection
- •treatment with HFNC
- •Estimated P/F ratio of ≤ 13 KPa
排除标准
- •language barrier
- •unable to provide consent
- •risk of deterioration due to study
研究组 & 干预措施
Intervention
An additional oxygen mask was applied for 30 minutes, in patients with ongoing HFNC treatment.
干预措施: oxygen mask (Other)
结局指标
主要结局
Oxygenation
时间窗: 30 minutes
Change in SaO2 in % from ABG with mask vs without mask
次要结局
- Carbon dioxide(30 minutes)
- SpO2(60 minutes)
- Respiratory rate(30 minutes)
研究者
Gustav Torisson
Principal Investigator
Region Skane