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临床试验/NCT02888509
NCT02888509Unknown不适用

Neural and Cognitive Mechanisms of Depression and Anxiety: a Multimodal MRI Study

University of Electronic Science and Technology of China1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2015年6月最近更新:
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适应症

试验速览

阶段
不适用
发起方
入组人数
150
试验地点
1
主要终点
Brain structural and functional changes in patients
研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

To explore the neural and cognitive mechanisms of depression (including unipolar depression and Bipolar disorder) and anxiety using multimodal MRI techniques.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
16 Years 至 55 Years（Child, Adult）
性别
All
接受健康志愿者
是

入选标准

  • •Age range from 16 to 55 years old.
  • •All patients were interviewed by two experienced psychiatrists using the Structured Clinical Interview for DSM-IV (patient edition)

排除标准

  • •Schizophrenia, mental retardation or personality disorder, any history of loss of consciousness, substance abuse, serious medical or neurological illness.
  • •Subjects with contraindications to MRI

结局指标

主要结局

Brain structural and functional changes in patients

时间窗: one time point

Structure and function changes in patients will be assessed by Voxel-based morphometry analysis for structural changes, as well as Regional homogeneity, Amplitude of lowfrequency fluctuation, etc, for functional changes.

次要结局

未报告次要终点

研究者

发起方
University of Electronic Science and Technology of China
申办方类型
Other
责任方
Principal Investigator
主要研究者

chenhuafu

professor

University of Electronic Science and Technology of China

研究点 (1)

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Neural and Cognitive Mechanisms of Depression and... | 临床试验