Brain Imaging of Psychotherapy for Depression (Includes, "Reward System Recovery Following Behavioral Activation Therapy in Depression")

University of North Carolina, Chapel Hill1 site in 1 country27 target enrollmentOctober 2006

ConditionsMajor Depressive Disorder

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Major Depressive Disorder
Sponsor: University of North Carolina, Chapel Hill
Enrollment: 27
Locations: 1
Primary Endpoint: Functional Magnetic Resonance Imaging
Status: Completed
Last Updated: 13 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of the proposed research is to examine the neural correlates of depressive symptom reduction in individuals with major depressive disorder using functional magnetic resonance imaging (fMRI), and to compare results to those obtained from a nondepressed control group.

Registry

clinicaltrials.gov

Start Date

October 2006

End Date

January 2008

Last Updated

13 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

University of North Carolina, Chapel Hill

Responsible Party

Principal Investigator

Gabriel Dichter

Associate Professor of Psychiatry

University of North Carolina, Chapel Hill

Eligibility Criteria

Inclusion Criteria

•For group 1: Diagnosis of current depression and no other current Axis I psychiatric disorder
•For group 1: Hamilton Depression Rating Scale score of 15 or greater

Exclusion Criteria

•A history of serious head injury or neurological disease or psychosis
•Current use of psychoactive medications
•Factors that could affect MRI safety including current or planned pregnancy
•For group 2: current Axis I psychiatric disorder, as assessed by structured clinical interview