NCT04369950已完成4 期
Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine
The University of Texas Health Science Center, Houston1 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2020年5月11日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Total Amount of Opioid Used
研究概览
简要总结
The purpose of this study is to show that the effect of 3% 2-chloroprocaine prior to epidural morphine administration will be not inferior to the effect of epidural 2% lidocaine with 1:200,000 epinephrine on total opioid use for 24h
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •pregnant patients
- •live singleton pregnancy
排除标准
- •obstructive sleep apnea
- •drug abuse
- •chronic pain
- •chronic opioid use
- •nonfunctioning epidural
研究组 & 干预措施
3 percent 2-Chloroprocaine and epidural morphine
Experimental
干预措施: 3% 2-chloroprocaine and epidural morphine (Drug)
结局指标
主要结局
Total Amount of Opioid Used
时间窗: 24 hours after epidural morphine administration
次要结局
- Total Amount of Opioid Used(4 hours after epidural morphine administration)
- Number of Participants Who Had Mild, Moderate or Severe Nausea as Measured by a 3 Point Scale(4,8, 12 and 24 hours after epidural morphine administration)
- Number of Participants Who Had Mild, Moderate or Severe Pruritis as Measured by a 3 Point Scale(4,8, 12 and 24 hours after epidural morphine administration)
- Time Until First Opioid Request(Up to 48 hours after epidural morphine administration)
- Pain as Measured by a 11 Point Verbal Scale(4,8, 12 and 24 hours after epidural morphine administration)
研究者
Linden Lee
Assistant Professor
The University of Texas Health Science Center, Houston
研究点 (1)
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