A Comparison of platelet to albumin ratio and serum Neutrophil gelatinase-associated lipocalin (NGAL) to predict AKI in patients with sepsis: an Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- To evaluate the role of PAR and serum NGAL in predicting AKI in patients with sepsis admitted to ICU
研究概览
简要总结
My study, "A Comparison of Platelet-to-Albumin Ratio and Serum Neutrophil Gelatinase-Associated Lipocalin (NGAL)to Predict AKI in Patients with Sepsis," An observational study will be carriedout in the Adult Intensive Care Unit of All India Institute of Medical Sciences, the study will include all patients of age >= 18 years with sepsis. Patientswith repeated ICU admission and pre-existing renal disease shall be excluded.The research question is to find out whether PAR has a similar diagnostic andprognostic value as serum NGAL to predict AKI.
The study aims to investigate the role of PAR andurinary NGAL in predicting AKI in patients admitted to the ICU with sepsis. Theexpected outcome is to define an optimum cut-off value of PAR andserum NGAL for diagnosing sepsis & to prognosticate the outcome of sepsis,which helps in the early identification of AKI and thus early intervention andmanagement.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Inclusion criteria: 1.Patients with sepsis 2.Age more than 18 years.
排除标准
- •Exclusion criteria: 1.Multiple ICU admissions 2.Pre-existing renal disease 3.Missing data.
结局指标
主要结局
To evaluate the role of PAR and serum NGAL in predicting AKI in patients with sepsis admitted to ICU
时间窗: At the time of admission (baseline) and at the time of development of acute kidney injury (AKI) according to KDIGO criteria
次要结局
- 1. To establish an optimum cut-off value for PAR & serum NGAL for diagnosing sepsis & to prognosticate the outcome of sepsis.(2. Evaluation of the combined value of PAR & NGAL for predicting the development of AKI in sepsis)