NCT06939387招募中不适用
Establishment, Evaluation and Treatment Strategy of Drug-induced Kidney Injury Model
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,500
- 试验地点
- 1
- 主要终点
- Model performance metrics assessed by AUC-ROC, accuracy and F1-score using 10-fold cross-validation
研究概览
简要总结
To establish the prediction model of renal dysfunction in patients with drug-induced renal injury and study the prognosis of different drug treatments
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Drug-induce acute kidney injury
排除标准
- •1.Dialysis patients; 2.No baseline creatinine; 3.Obstructive AKI; 4.Clinical data were incomplete.
结局指标
主要结局
Model performance metrics assessed by AUC-ROC, accuracy and F1-score using 10-fold cross-validation
时间窗: through study completion, an average of 6 months
The prognosis of renal function was evaluated by measuring creatinine and proteinuria by laboratory tests. Predict outcomes using machine learning methods. And the prediction effect of the prediction model was evaluated by AUC-ROC, F1, accuracy and other indicators.
次要结局
- The rate at which creatinine falls(7 days, 1 month, 3 months after treatment)
研究者
研究点 (1)
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