Using Novel Behavioral Economic Measures to Characterize Dual Marijuana and Tobacco Use in Young Adults
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Change in self-reported cannabis craving
研究概览
简要总结
The multi session experimental study aims to determine dual use patterns of marijuana and tobacco by assessing the impact of price and availability of marijuana and tobacco using a cross price elasticity of demand task. The study will recruit 120 non-treatment seeking emerging young adults (18-25 years) who smoke marijuana and tobacco.
详细描述
Young adulthood is a crucial time to study substance use disorders which increase cancer risk later in life. It is especially important to understand marijuana and tobacco use as most young adults often use both. Although dual use is related with increased long-term health and behavioral risks, underlying behavioral mechanisms remain unclear. This study aims to address this gap by using rigorous laboratory-based behavioral economic measure including a novel cross-price elasticity of demand (CPED) task and an innovative extension of cue-induced demand to assess cross-cue reactivity to better understand co- use. The results will help lead cessation efforts in this population and reduce cancer risk across the lifespan. Participants (N = 120) will be young adults (age 18-25) endorsing current tobacco and marijuana use and will complete 4 experimental in-person sessions. Following a phone-screen to assess preliminary eligibility, participants will come to the study center for in-person baseline screening. This screening consists of a urine toxicology screen, a breathalyzer test, and self-report questionnaires. The remaining three sessions will be completed in person which mainly consist of cross-cue reactivity sessions, self-report measures, and a qualitative exit interview following the final session.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Males/females who are 18 to 25 years of age
- •Young adults who currently smoke commercial tobacco cigarettes (≥1x weekly in the past 30 days and for the past six months)
- •Young adults who currently smoke marijuana (≥4 times in past 30 days and at least weekly on average for the last six months)
- •Participants must report purchasing their own tobacco and marijuana at least once in the past 6 months
- •Participants must speak, comprehend, and read English.
排除标准
- •Intention to quit marijuana or tobacco use in the next 30 days
- •Self-reported illicit drug or heavy episodic alcohol use on >20 days in the past month (excluding marijuana)
- •Individuals who are pregnant or breastfeeding
- •Positive saliva test for recent THC use
- •Breath alcohol level above 0 at any session.
- •Participants who exclusively roll their own tobacco cigarettes
研究组 & 干预措施
Cue Reactivity
Participants will be exposed to neutral followed by cannabis or tobacco cues in a fixed sequence while they answer questions about their subjective state. The cues will include everyday items (e.g., eraser) and cannabis-related items (e.g., lighter).
干预措施: Cue Reactivity (Behavioral)
结局指标
主要结局
Change in self-reported cannabis craving
时间窗: Up to 40 days post-baseline session
This study utilizes a structured cannabis cue exposure paradigm. During cue exposure, participants rate subjective craving on a scale from 0, "Not at all," to 10, "Extremely." Cannabis craving will be assessed following neutral cue exposure and then cannabis cue exposure. The primary outcome will be change in cannabis craving.
Change in self-reported tobacco craving
时间窗: Up to 40 days post-baseline session
This study utilizes a structured tobacco cue exposure paradigm. During cue exposure, participants rate subjective craving on a scale from 0, "Not at all," to 10, "Extremely." Tobacco craving will be assessed following neutral cue exposure and then tobacco cue exposure. The primary outcome will be change in tobacco craving.
次要结局
未报告次要终点