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临床试验/NCT03666676
NCT03666676已完成不适用

Auditory Processing of Complex Sounds - Sensitivity to Chirps

University of Rochester1 个研究点 分布在 1 个国家目标入组 67 人开始时间: 2020年6月9日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
67
试验地点
1
主要终点
F2 Discrimination Threshold

研究概览

简要总结

The purpose of this study is to better understand the sensitivity of listeners to the fast changes in frequency or amplitude of sounds that occur in speech. The investigators are studying ways to manipulate these aspects of sounds in an effort to make speech sounds more clear.

详细描述

The investigators will test listeners with normal hearing or with mild or moderate hearing loss. Tests will first focus on sensitivity to changes in fast changes in amplitude (loudness) or frequency (pitch) in sounds. Then the investigators will test the intelligibility of synthetic vowels and syllables in which these "chirps" are manipulated. Finally, the investigators will test intelligibility of words in noise while manipulating sounds in an effort to improve clarity.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Normal hearing, mild or moderate symmetric sensorineural hearing loss.

排除标准

  • •Asymmetric hearing thresholds (more than 15 decibels (dB) threshold difference between the two ears at any frequency up to 4 kHz).
  • •Severe hearing loss (greater than 60 dB hearing thresholds at any frequency up to 4 kHz).

研究组 & 干预措施

Normal Hearing

Active Comparator

Signal processing to improve intelligibility

干预措施: Signal processing to improve intelligibility (Other)

Mild hearing loss

Active Comparator

Signal processing to improve intelligibility

干预措施: Signal processing to improve intelligibility (Other)

Moderate hearing loss

Active Comparator

Signal processing to improve intelligibility

干预措施: Signal processing to improve intelligibility (Other)

结局指标

主要结局

F2 Discrimination Threshold

时间窗: 6 month

Discrimination thresholds in % frequency for F2, the higher-frequency peak in synthetic vowel stimuli.

F1 Discrimination Threshold

时间窗: 6 months

Discrimination threshold for changes in F1, the low-frequency formant (spectral peak) in the synthetic vowel sounds.

Pure-tone Average Thresholds

时间窗: 6 months

Hearing thresholds, average across test frequencies from 250 to 4000 Hz and averaged across the two ears.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Laurel Carney

Professor

University of Rochester

研究点 (1)

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