When Triage is Insufficient - the Benefit of Bedside CRP Within Ambulance Care
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 110
- 主要终点
- Number of patients with high suPAR level
研究概览
简要总结
Patients with degreased (DGC) for ambiguous reasons receive low triage priority. Their death risk is triple. Tools are needed to identify the critically ill patients from this group. The triage used today is not effective. The bedside point-of-care measurements are CRP, lactate acid and suPAR (Soluble Urokinase Plasminogen Activator Receptor). Elevated values associate with the probability of critical illness and predict a risk of death.
详细描述
Purpose: To improve identification and proper prioritization of patients with non-specific symptoms prehospitally, we intend to investigate whether Q-CRP, a rapid test for CRP, correlates with time-critical states in the above-mentioned patient group alone or together with CRP, lactate and suPAR. The primary endpoint is need for hospital care.
Material: Patients over 18 years who exhibit non-specific symptoms and transported to the emergency room.
Method: In patients with unspecified conditions, defined according to the inclusion template, a venous blood sample was taken prehospitally at the scene by the EMS.
Analysis: Significance tests and regression analyzes with 95% CI were used. The diagnostic accuracy of Q-CRP, lactate, suPAR and combinations thereof were compared with optimal boundary values.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 16 Years 至 104 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over 18 years who exhibit non-specific symptoms and transported to the emergency room.
排除标准
- •Abnormal vitals
结局指标
主要结局
Number of patients with high suPAR level
时间窗: 24 hours
A high suPAR level, e.g. above 6 ng/ml
次要结局
未报告次要终点
研究者
Marja Mäkinen
PhD, principal investigator
Helsinki University Central Hospital