Reliability, Validity, and Responsiveness of Shearwave Elastography to Assess Muscle Stiffness in Neurological Population With Muscle Overacivity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- reliability, validity and responsiveness shearwave elastography (SWE) to assess muscle elasticity
研究概览
简要总结
Objective:
- to investigate reliability, validity and responsiveness of shearwave elastography (SWE) to assess muscle stiffness of overactive upper or lower limb muscles in different angle joint positions in patients with neurological condition
- to investigate the relationship between muscle stiffness measured by SWE and by MyotonPro
- to investigate the correlation between muscle stiffness measured by SWE and clinical outcomes
Methods: each patient will be assessed three times: two times at an interval of 15 minutes on the same day and one time at an interval of one week at the same time of the day. The following measurements will be made at each evaluation: SWE, MyotonPro, clinical evaluation. SWE and MytotonPro will be taken at different angle joint position.
Outcomes: muscle stiffness measured by SWE and MyotonPro at different angle joint positions, and clinical evaluation (passive range of motion, modified ashworth scale, tardieu scale, fuglmeyer) Hypothesis: SWE is a valid, reliable, and resposive method to assess muscle stiffness in neurological population with muscle overactivity. The results of SWE will be correlated with the results of MyotonPro and with clinical outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age > 18 years
- •hemiparesia/-plegia following neurological condition (TBI, stroke,...)
- •> 3 months after injury
- •muscle overactivity in lower limb
排除标准
- •other neurological or orthopaedic conditions involving the affected limb
- •aphasia or major cognitive impairment limiting functional assessment
- •botulinum toxin injection in the last 3 months
- •previous treatment of muscle overactivity with surgical procedures.
结局指标
主要结局
reliability, validity and responsiveness shearwave elastography (SWE) to assess muscle elasticity
时间窗: Day 1 + 7-14 days
expressed in m/s. A smaller shearwave velocity indicates a better outcome
次要结局
- muscle stiffness assessment with MyotonPro(two times day 1 at 15minutes interval + 7-14 days later at same time of the day)