The Immediate Effect of Applying Transcutaneous Electrical Nerve Stimulation (TENS) on Sympathetic Ganglion and Gastrocnemius for Popliteal Blood Flow
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- Doppler ultrasound measurement of changes in popliteal fossa blood flow
研究概览
简要总结
This study aims to evaluate the immediate hemodynamic effects of transcutaneous electrical nerve stimulation (TENS) on the popliteal artery and vein. Vascular issues like PAOD and DVT are common in patients with diabetes, obesity, or immobility due to increased resistance and reduced blood flow. Traditional treatments (medication or surgery) are not always feasible, prompting interest in TENS as an alternative. Although primarily used for pain relief, TENS may enhance blood flow. This research compares different stimulation frequencies (80 Hz vs. 4 Hz) and sites (gastrocnemius muscle vs. thoracolumbar sympathetic ganglia) to identify the most effective configuration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy people
- •Age: 18 years and above (inclusive)
- •Body mass index (BMI) between 18.5 and 24
排除标准
- •Unable to complete two interventions within a week
- •Have contraindications to electrotherapy (for example: metal implants in the body, open wounds, pregnancy, sensory loss)
- •Obvious varicose veins
- •Unable to lie down for about 1 to 2 hours
- •Taking drugs or nutritional supplements that affect autonomic nervous activity or vasodilation (for example: Ginkgo biloba)
- •Ankle and Ankle Index (ABI) less than 0.9 or greater than 1.3
研究组 & 干预措施
Sympathetic Ganglia with Low-Frequency Electrical Stimulation
Sympathetic Ganglia (T12.L1.L2) Low-Frequency Electrical Stimulation (4Hz) electrical stimulation:15-minute
干预措施: Transcutaneous Electrical Nerve Stimulation，TENS (Device)
Sympathetic Ganglia with High-Frequency Electrical Stimulation
Sympathetic Ganglia (T12.L1.L2) Low-Frequency Electrical Stimulation (80Hz) electrical stimulation:15-minute
干预措施: Transcutaneous Electrical Nerve Stimulation，TENS (Device)
gastrocnemius with Low-Frequency Electrical Stimulation
gastrocnemius with Low-Frequency Electrical Stimulation Low-Frequency (4Hz) electrical stimulation:15-minute
干预措施: Transcutaneous Electrical Nerve Stimulation，TENS (Device)
gastrocnemius with high-Frequency Electrical Stimulation
gastrocnemius with high-Frequency Electrical Stimulation high-Frequency(80Hz) electrical stimulation:15-minute
干预措施: Transcutaneous Electrical Nerve Stimulation，TENS (Device)
结局指标
主要结局
Doppler ultrasound measurement of changes in popliteal fossa blood flow
时间窗: 45 minutes
Using Doppler ultrasound to measure blood flow before, during, immediately after, and 15 minutes after electrical stimulation to observe the effects of electrical stimulation on blood flow.
次要结局
- heart rate(45 minutes)
研究者
Mengjie Shen
graduate student
Kaohsiung Medical University