临床试验/NCT03177408

NCT03177408Unknown不适用

Impact of HMGB1 on Diastolic Dysfunction in Hypertensive Patients

Jing Li0 个研究点目标入组 100 人开始时间: 2017年8月15日最近更新: 2017年6月6日

适应症

试验速览

阶段: 不适用
发起方
入组人数: 100
主要终点: Differences of HMGB1 levels between hypertensive patients with and without diastolic dysfunction

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

This study evaluated the association between HMGB1 and diastolic dysfunction in hypertensive patients. HMGB1 level were tested in all patients, and diastolic function determined by echocardiographic.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Prospective

入排标准

年龄范围: 30 Years 至 70 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•All of the hypertensive patients in both diastolic dysfunction and control groups were either newly diagnosed or were aware of hypertension without using any pharmacotherapy.

排除标准

•Individuals already under treatment for hypertension were not include.

结局指标

主要结局

Differences of HMGB1 levels between hypertensive patients with and without diastolic dysfunction

时间窗: on the day of admission

Blood samples of all individuals are collected on the day of admission and HMGB1 levels are tested. Echocardiographic assessment is performed with echocardiography device by using 2.5-3.5 Mega Hertz(MHz) transducer in the lateral decubitis position.

次要结局

Differences of HMGB1 levels between grades of diastolic dysfunction(on the day of admission)

研究者

发起方

Jing Li

申办方类型

Other

责任方

Sponsor Investigator

主要研究者

Jing Li

Doctor

Affiliated Hospital of Hebei University

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