Nasopharyngeal Oxygen With Nose-close and Abdomen-compression in Pediatric Flexible Bronchoscopy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 156
- 试验地点
- 2
- 主要终点
- Heart rate (beat/min)
研究概览
简要总结
The nasopharyngeal oxygen (NPO) with Nose-close (NC) and Abdomen-compression (AC) technique may use for support or rescue asphyxiated infants during Flexible bronchoscopy.
详细描述
OBJECTIVES: To evaluate the efficacy of a novel cardiopulmonary resuscitation (CPR) technique-nasopharyngeal oxygenation with nose-close and abdomen-compression (NPO-NC-AC)-in small infants during flexible bronchoscopy (FB).
METHODS: Infants with body weight (BW) <5.0 kg and receiving nasal diagnostic or interventional FB (dFB, iFB) were enrolled. Under NPO (0.5 L/kg/min), when infant's heart rate (HR) <80 beats/min or oxygen saturation (SpO2) <85% for more than 10 seconds, rescue NC-AC was initiated. It was performed by (1) increased NPO flow to 0.5-1.0 L/kg/min; (2) NC 1 second for inspiration; and (3) AC 1 second for expiration with simultaneously released nostrils. Repeat doing steps (2) and (3) at a rate of 30 cycles/min until HR, SpO2, and blood pressure (BP) returned to normal. Cardiopulmonary parameters were monitored and analyzed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- — 至 20 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •body weight (BW) less than 5.0 kg;
- •receiving nasal approach flexible bronchoscopy.
排除标准
- •cannot nasal approach flexible bronchoscopy.
结局指标
主要结局
Heart rate (beat/min)
时间窗: Participants will continually monitoring by EKG for 2 days after the procedure.
During and after this FB procedure, vital signs are continually monitoring. When the heart rate (HR) \<80 beat/min (measured by continuouse wave and digit form of EKG monitor) and lasting \>10 seconds. Immediately rescued with rhythmic NC-AC. If the heart rate did not reach to its acceptable level (\>80 beat/min) within 2 minutes, then traditional CPR procedures involving bag-mask ventilation, ET intubation, Ambu bag ventilation or even chest compressions were substituted.
次要结局
- Oxygen saturation by pulse oximetry(Participants will continually monitoring by pulse oximeter for 2 days after the procedure.)
- Mean blood pressure (mmHg)(Participants will continually monitoring by sphygmomanometer for 2 days after the procedure.)
研究者
Cho-yu Chan, MD
Taipei Veterans General Hospital,Taiwan, Taipei Veterans General Hospital,Taiwan
Taipei Veterans General Hospital, Taiwan