TCTR20171106003
Recruiting
Phase 4
High flow nasal oxygen for prevention of intubation in acute non-hypercapnic hypoxemic respiratory failure in immunocompromised patients, a randomized trial
Faculty of medicine, Chiang Mai University0 sites74 target enrollmentNovember 6, 2017
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Acute hypoxemic respiratory failure due to pneumonia in immunocompromised patients
- Sponsor
- Faculty of medicine, Chiang Mai University
- Enrollment
- 74
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •all the following
- •1\.Immunocompromised patients: solid or hematologic malignancy, received immunosuppressive drug or steroid at a dose\> 20 mg/day of prednisolone for \> 30 days, HIV infection
- •2\.Require nasal low\-flow oxygen of 4 L/min to maintain PaO2 above 60 mmHg or SpO2\> 90% for \> 1 hour
- •3\.Age \>\= 18 years
Exclusion Criteria
- •1\.PaCO2\> 45 mmHg
- •2\.Post\-extubation respiratory failure (respiratory failure within 48 hr after extubation)
- •3\.Life\-threatening ARF requiring immediate IMV
- •5\.Active pulmonary tuberculosis
- •6\.Contraindications to NIV
- •7\.A do\-not\-intubate order
- •8\.Patients refused to participate the study
Outcomes
Primary Outcomes
Not specified
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