An Investigation Into an Objective Measure of Muscle Quality, Function and Ability
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Observation of healthy volunteer measurement of Electrical Impedance Myography in arm muscles.
研究概览
简要总结
The assessment of muscular function, quality and ability is of high importance in a diverse range of clinical disciplines from anaesthetics to physiotherapy. This study will look at the range of measurement techniques currently in use and development and considers their effectiveness and objectivity. It will also investigate whether an objective measurement technique can be found or developed that can be used both in the clinical environment and the community setting. This will focus on upper limb function and ability; ability is used here instead of strength since ability better describes functions needed for daily living rather than the maximum output a muscle is capable of.
详细描述
A literature review (available on request) explores what can be measured, the problems of measurement and its objectivity. The aim is to investigate whether there is a method of measuring muscle quality, function and ability that can be used objectively in the clinical environment or the community with equal ease or whether such a method can be developed.
The literature review identified electrical impedance myography (EIM) as a potentially objective technique to measure muscle quality and ability. Two hypotheses are proposed to test the objectivity:
The EIM measurement of passive and active muscle is not significantly different.
EIM measurements in younger and older adult volunteers is significantly different.
There is only one study visit for this study, so all study activities will occur on the same day at the Posture and Mobility Centre, Treforest or the Artificial Limb and Appliance Centre, Rookwood Hospital.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •be volunteers
- •be over the age of 18
- •no pre-existing neuromuscular disease
- •not have an implanted cardiac device
- •be well at the time of measurement
- •be able to give informed consent
排除标准
- •Any existing neuromuscular disorder (eg multiple sclerosis, ALS, MND, CP)
- •Any existing cardiac disease (including having a pacemaker or ICD)
- •Active arthritis
- •Be pregnant
- •Any other implanted electrical device
- •Not able to give informed consent
结局指标
主要结局
Observation of healthy volunteer measurement of Electrical Impedance Myography in arm muscles.
时间窗: One visit per volunteer. Data to be accumulated over approximately 1 year
Primary Objective To measure EIM in sketetal arm muscle. Measurements to be made when the muscles are passive and when they are contracted. EIM measurements are reactance and resistance which are both measured in Ohms. At least 20 eligible and consented volunteers to be recruited and measured. To be measured at the one healthy volunteer visit. No other visits are part of the study.
次要结局
- Fitness health measure of participants(through study completion, an average of 1 year)
- Age of participants(through study completion, an average of 1 year)
研究者
Stephanie Wentworth
Chief Investigator
Cardiff and Vale University Health Board