Evaluation of the Effectiveness of YAG Laser Iridotomy in Patients With Primary Angle-Closure: Temporal Peripheral Iridotomy Compared to Inferior Peripheral Iridotomy
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- adverse events
研究概览
简要总结
This study evaluates the effectiveness and safety of YAG laser peripheral iridotomy performed at two different locations (temporal and inferior) in patients with primary angle-closure glaucoma, a leading cause of blindness worldwide. Patients visiting the glaucoma clinic at Feiz Hospital who are candidates for peripheral iridotomy will participate. In each patient, one eye will receive a temporal iridotomy, and the other eye will receive an inferior iridotomy, with patients unaware of the location used in each eye. The study will measure outcomes such as laser power, intraocular pressure, visual symptoms, and complications over six months to determine which approach is more effective and safer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 24 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of Primary Angle-Closure Glaucoma.
- •Adults (typically over 40 years old).
- •Ability to provide informed consent.
- •Narrow or closed anterior chamber angle (based on gonioscopy).
- •Intraocular pressure (IOP) controlled with medication but requiring surgery.
- •No previous iridotomy.
排除标准
- •econdary glaucoma.
- •Active eye diseases (e.g., infection or inflammation).
- •Advanced cataracts or lens-related issues.
- •Severe visual impairment (e.g., less than 20/200 vision).
- •Uncontrolled systemic diseases (e.g., diabetes or cardiovascular disease).
- •Pregnancy or breastfeeding.
- •Previous eye surgery (except for minor procedures).
- •Inability to follow-up with scheduled visits.
结局指标
主要结局
adverse events
时间窗: 1 day, 1 week, 1month
Surgical and postoperative complications (e.g., bleeding, infection, or changes in intraocular pressure).
次要结局
未报告次要终点
研究者
Afsaneh Naderi Beni
IsfahanUMS
Isfahan University of Medical Sciences