CTRI/2018/02/012134已完成未知
Efficacy and safety of combined oral chelation with deferiprone and deferasirox on iron overload in children with transfusion dependent thalassemia
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- JIPMER
- 入组人数
- 23
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •Children of age 2-18 years with thalassemia and serum ferritin >= 1500ng/ml
排除标准
- •Children with
- •1. Serum creatinine more than two times the upper limit for age
- •2. Serum aspartate amino transferase and alanine amino transferase more than five times the upper limit for age
- •3. Children with absolute neutrophil count less than 1500/mm3 and platelets less than 1 lakh/mm3
- •4. Significant proteinuria defined by protein creatinine ratio more than 0.5
- •5. Cardiac failure secondary to myocardial iron toxicity
- •6. Previous history of allergic reaction to deferiprone or deferasirox
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